RARECHEM AL BO 1567

RARECHEM AL BO 1567 - Names and Identifiers

Name	3-(2,6-Dichlorophenyl)-5-methylisoxazole-4-carboxylic acid
Synonyms	RARECHEM AL BO 1567 Dicloxacillin EP Impurity D 3-(2,6-dichlorophenyl)-5-methy 3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolecarboxylicaci 3-(2,6-DICHLOROPHENYL)-5-METHYL-OXAZOLE-4-CARBOXYLIC ACID 3-(2,6-DICHLOROPHENYL)-5-METHYLISOXAZOLE-4-CARBOXYLIC ACID 3-(2,6-Dichlorophenyl)-5-Methyllisoxazole-4-CarboxylicAcid 3-(2,6-Dichlorophenyl)-5-methylisoxazole-4-carboxylic acid 5-METHYL-3-(2',6'-DICHLOROPHENYL)-4-ISOXAZOLECARBOXYLIC ACID
CAS	3919-76-4
EINECS	223-487-3

RARECHEM AL BO 1567 - Physico-chemical Properties

Molecular Formula	C11H7Cl2NO3
Molar Mass	272.09
Melting Point	221 °C
Storage Condition	Room Temprature
MDL	MFCD00051658
Use	Use the intermediate of diclofenac sodium penicillin.

RARECHEM AL BO 1567 - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed
Safety Description	S22 - Do not breathe dust. S36/37 - Wear suitable protective clothing and gloves. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

RARECHEM AL BO 1567 - Upstream Downstream Industry

Raw Materials	Hydroxylamine hydrochloride Acetoxyacetic acid BENZAL CHLORIDE Ethyl 5-methylisoxazole-4-carboxylate
Downstream Products	3-(2,6-Dichlorophenyl)-5-methylisoxazole-4-carbonyl chloride

RARECHEM AL BO 1567 - Nature

storage conditions	Sealed in dry,2-8°C
BRN	806524
EPA chemical information	4-Isoxazolecarboxylic acid, 3-(2,6-dichlorophenyl)-5-methyl- (3919-76-4)

Last Update：2024-04-10 22:29:15

RARECHEM AL BO 1567 - Production method

Use 6-dichlorotoluene to chlorinate under the catalysis of chlorine and phosphorus trichloride to generate 2,6,α,α-tetrachlorotoluene, and then oxime with hydroxylamine hydrochloride under the action of concentrated sulfuric acid to obtain 2,6-dichlorobenzene oxime, and then chlorinated to obtain 2,6-dichlorobenzene oxime chloride, and then cyclize with ethyl acetoacetate to form, ethyl 6-dichlorophenyl)-5-methyl-4-isoxazole formate. The latter is hydrolyzed with alkali and acidified to obtain the product.

Last Update：2024-04-10 22:29:15